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The ever-growing Interest in natural product chemistry is indicated by the success of specialist journals in the field, and by the flood of natural product related papers in all the mainstream journals of organic chemistry. This book reviews in a concise and manageable way the progress in all key areas since 1983. Very heavily referenced, the most significant advances are highlighted over a wide field of chemistry, structure, synthesis and biosynthesis. The book provides a unique entry into the vast literature on this subject for researchers and lecturers interested in natural products and synthetic organic chemistry.
Subjects of the book :
Chemistry
Contents of the book :
chapter 1 Carbohydrates
1.1 Introduction
1.2 Recent developments in O-glycosidation methodology
1.3 Recent developments in C-glycoside synthesis
1.4 Synthesis of antibiotic sugars
1.5 Use of carbohydrates as chiral templates and reagents for asymmetric synthesis
1.6 Use of carbohydrates as chiral starting materials for the synthesis of
enantiomerically pure natural products
References
chapter 2 Aromatic compounds
2.1 Introduction
2.2 Benzenoids
2.3 Coumarins
2.4 Isocoumarins, chromanones, chromones and cannabinoids
2.5 Macrocyclic lactones
2.6 Pyrones, butenolides, lignans and benzofurans
2.7 Terphenyls
2.8 Flavonoids
2.9 Xanthones and benzophenones
2.10 Naphthalenes and naphthoquinones
2.11 Anthraquinones
2.12 Anthracyclines
2.13 Some other Polycyclic antibiotics
2.14 Ansamycins
References
chapter 3 Terpenoids
3.1 Introductions
3.2 Monoterpenoids
3.3 Sesquiterpenoids
3.4 Diterpenoids
3.5 Sesterterpenoids
3.6 Triterpenoids
3.7 Carotenoids
References
chapter 4 Steroids
4.1 Introduction
4.2 Molecular rearrangement
4.3 Remote functionalisation
4.4 Photochemical reactions
4.5 Partial synthesis
References
chapter 5 Amino acids, peptides and proteins
5.1 Introduction
5.2 Amino acids
5.3 Peptides
5.4 Techniques for structural elucidation
5.5 Proteins
5.6 Appendix
References
chapter 6 Alkaloids
6.1 Introduction
6.2 Biomimetic studies
6.3 Synthesis
6.4 Marine alkaloids
References
chapter 7 Nucleosides, nucleotides and nucleic acids
7.1 Introduction
7.2 Nucleosides
7.3 Nucleotides
7.4 Nucleic acids
7.5 Supplementary reading
References
chapter 8 Porphyrins
8.1 General introduction
8.2 Macrocycle biosynthesis
8.3 Haemoprotein model compounds
8.4 Porphyrins with easily oxidisable substituents
8.5 Utilisation of porphyrin excited states
8.6 Porphyrins in photodynamic therapy
8.7 DNA-porphyrin interactions
8.8 Porphyrins as novel materials
8.9 Prophyrins with liquid crystalline properties
References
chapter 9 Aliphatic compounds
9.1 Introduction
9.2 Semiochemicals
9.3 Development of synthetic technology
9.4 Marine natural products
9.5 Enyne-allene and enediyne antibiotics
References
Chemical abbreviations and acronyms
IndexISBN - 9788181288639
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Pages : 468
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