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Description: Molecular Biology is a rapidly advancing field with a constant flow of new information and cutting-edge developments that impact our lives. Lewin’s GENES has long been the essential resource for providing the teaching community with the most modern presentation to this dynamic area of study. Lewin"s GENES XI continues this tradition by introducing the most current data from the field, covering gene structure, sequencing, organization, and expression. A wealth of subject-matter experts, from top institutions, to provide content updates and revisions in their individual areas of study. A reorganized chapter presentation provides a clear, more student-friendly introduction to course material than ever before. .
New and Key Features of Lewin"s GENES XI:
• Updated content throughout to keep pace with this fast-paced field.
• Reorganized chapter presentation provides a clear, student-friendly introduction to course material.
• Expanded coverage describing the connection between replication and the cell cycle is included, and presents eukaryotes as well as prokaryotes.
• A wealth of pedagogical features throughout the text help student better understand and retain important data
Contents:
Part 1: Genes and Chromosomes
Chapter 1: Genes Are DNA • Introduction • DNA Is the Genetic Material of Bacteria and Viruses • DNA Is the Genetic Material of Eukaryotic Cells • Polynucleotide Chains Have Nitrogenous Bases Linked to a Sugar–Phosphate Backbone • Supercoiling Affects the Structure of DNA • DNA Is a Double Helix • DNA Replication Is Semi conservative • Polymerases Act on Separated DNA Strands at the Replication Fork • Genetic Information Can Be Provided by DNA or RNA • Nucleic Acids Hybridize by Base Pairing • Mutations Change the Sequence of DNA • Mutations May Affect Single Base Pairs or Longer Sequences • The Effects of Mutations Can Be Reversed • Mutations Are Concentrated at Hotspots • Many Hotspots Result from Modified Bases • Some Hereditary Agents Are Extremely Small • Summary • References
Chapter 2: Genes Encode RNAs and Polypeptides • Introduction • Most Genes Encode Polypeptides • Mutations in the Same Gene Cannot Complement • Mutations May Cause Loss of Function or Gain of Function • A Locus May Have Many Different Mutant Alleles • A Locus May Have More Than One Wild-Type Allele • Recombination Occurs by Physical Exchange of DNA • The Genetic Code Is Triplet • Every Coding Sequence Has Three Possible Reading Frames • Bacterial Genes Are Colinear with Their Products • Several Processes Are Required to Express the Product of a Gene • Proteins Are trans-Acting but Sites on DNA Are cis-Acting • Summary • References ISBN - 9789380853710
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Pages : 968
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