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Although many general genetics and molecular biology text-book are avialable few recent textbook focus on microbial genetics. Since the fisrt edition was published, there have been numerous advances in microbial genetics. The development of new techniques such as polymerase chain reactian and electroportion made it possible to do molecular genetics in a variety of interesting and important bacteria that were previously genetically intractable.Genetic approaches have been essential for dissecting important microbiological problems, such as the mechanisms of virulence of bacterial pathogens and the emergence of antibiotic-resistant pathogens. Genetic analysis of Arachaea ( previously called Archabebacteria) has contributed to our understanding of evolution of the major groups of living organisms and the diversity of life. Each of these advance requird a solid knowledge or classic microbial genetics and modern molecular biology. We tried to include Archea when relevant, however, and we hope these sections will be expanded in the future. Thus, because the content is not strictly limited to bacteria, we retained the original title. Some sections are extensively rewritten, but we retained the basic formate, organization, and style of the first edition. * Contents : Part I : ESSENTIALS OF GENETICS AND MICROBIOLOGY. Essential fo Genetics. Nucleic Acids. Proteins. Bacteria. Part II : MOLECULAR ASPECTS OF GENE EXPRESSION. Gene Expression Regulation of Gene Expression. Part III :MAINTENANCE OF GENETIC INFORMATION. DNA. Replication. DNA Damage and Repair. Mutagenesis, Mutations, and Mutants. Part IV : GENETICS OF BACTERIAL AND PHAGES. Pladmids. Transposable Elements. Bacterial Transformation. Bacterial Conjugation. Genetics of Phage T4. Lytic Growth of phase. Lysogeny, Transduction. Strain Constrution. Part 5 : THE NEW MICROBIAL GENETICS. Genetic Engineering. Applications of Genetic Engineering. 1994 PB
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