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Description: Modern Pharmaceutical Industry: A Primer comprehensively explains the broad range of divisions in the complex pharmaceutical industry. Experts actively involved in each component discuss their own contribution to a pharmaceutical company’s work and success. Divisions include regulatory affairs, research and development, intellectual property, pricing, marketing, generics, OTC, and more. The seventeen chapters included in this resource offer a wide range of topics, from discovery and formulation to post-approval and legal. Readers will be given a detailed look at the structure of a contemporary drug company and a thorough understanding of what goes on behind the scenes.
Modern Pharmaceutical Industry: A Primer is a valuable resource for all pharmacy students, new hires at pharmaceutical companies, drug company management, and academic health center libraries. No other text provides a comprehensive look at one of the most dynamic industries related to the modern healthcare system.
Contents:
Chapter 1: Drug Discovery: New Compounds • Then and Now • Drug and Receptor • Modeling Molecules • Picturing Molecules • Picturing Interacting Molecules • Selection of Preferred Models • The Need for Crystals • The Double Helix and All That • Determining Nucleotide Sequences • From DNA to Protein • Converting DNA Sequences to Genomes • Structural Genomics • Genomes to Proteomes • Purifying Proteins and Growing Crystals • High-Throughput Systems for Growing Crystals • New and Novel Proteins • Fitting Drug to Receptor in Silico and Culling Misfits • High-Throughput Chemistry: Combinatorial Synthesis: A Combinatorial Example • High-Throughput Chemistry: Parallel Synthesis • Automated Cleanup • Product Characterization • Structural Genomics Leads to Structural Proteomics • Target Selection Through Structural Proteomics • High-Throughput Binding Studies • Assemble a Mouse • High-Throughput Screening: G-Protein-Coupled Receptors: Structure of G-Protein-Coupled Receptors . • Monitoring Transfection • Validating Target Receptors • References.ISBN - 9789380108469
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Pages : 342
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